Alzheimer's Research Studies

• As more people live to advanced old age it is critical to gain a greater understanding of their health status and functional abilities during their life in relation to aging and cognition as a whole. Knowledge gained from the Longevity Study will have a great impact in our understanding of the continual aging spectrum.
• This study is currently enrolling individuals, who are 50 years old and above who are willing to share information about their life.  There is a wait list to enroll into the study with the oldest individuals called first.

The overall goal of this NIH funded project is to adapt a validated digital health intervention called Medication Education, Decision Support, Reminding, and Monitoring (MEDSReM) system (IRB: 22546), currently designed to improve hypertension medication adherence in cognitively normal older adults, to support self-management of hypertension medication for persons with mild cognitive impairment (PwMCI).

MindCrowd is a first-of-its-kind web-based memory study to identify cognitive performance outliers and to better understand their genetic differences. In Phase I, the goal is to have 1 million individuals, aged 18+, take the 10-minute online test and gather information for a more detailed Phase II study. 

The National Institute of Aging (NIA) - Family Based Study - Early Onset Alzheimer’s Disease (FBS EOAD) is a study to understand the genetic factors influencing early-onset Alzheimer disease (EOAD) risk. The study includes individuals with EOAD, mild cognitive impairment, or other dementias. The study also recruits additional family members without dementia or memory problems that are willing to participate.

The POLARIS-AD clinical research study is for people who have early symptoms of Alzheimer’s disease and mild cognitive impairment. The study will test a new investigational medication to learn if it can slow or reverse early symptoms of Alzheimer’s disease.

BrainCheck is looking for adults 60 and older with memory impairment to play brain games!

Contribute to cognitive health research by taking brain games on your smartphone.

Do you or your partner live with dementia? University of Michigan researchers want to learn about how daily experiences and sleep patterns influence well-being and brain health!

SLEEPMATE aims to find out whether a tailored cognitive behavioral therapy for insomnia intervention can improve sleep for both persons living with cognitive changes and their caregivers. Sleep disturbances are highly prevalent in these pairs, and they increase the risks for many psychological and cognitive health issues for both persons. This research will help to determine if the behavioral intervention plan provided is practical and useful for pairs experiencing sleep problems.

PPMI seeks to understand how Parkinson’s disease starts and changes over time, who gets it and why. It follows people both with and without Parkinson’s to learn more about these processes. The overall goal of PPMI is to identify markers of disease progression for use in clinical trials for new drug development to treat or even prevent PD before it begins.

The Staying Connected through Communication Study is a survey for people who have noticed a change in their thinking and memory and are concerned about, or have a diagnosis of early stage dementia or mild cognitive impairment (MCI). This study also includes family members and/or friends of people with MCI or dementia.