ReCOGNITION - Multiple Sites

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ReCOGNITION - Multiple Sites


Study Status:
Recruiting
Age:
60 to 85
Study Type:
Caregiver Studies
Studies for People with Memory Impairment

Eligibility Requirements:

•    You must be diagnosed with mild dementia due to Alzheimer’s disease and have experienced a cognitive decline over at least 6 months
•    You must not have an alternative cause for dementia other than Alzheimer’s disease
•    You must have a caregiver who is willing to attend all study visits
 

About the Study:

This study aims to investigate the safety and effectiveness of investigational drug (Piromelatine) for people diagnosed with mild Alzheimer’s. The trial consists of a 28 week study to compare Piromelatine to placebo. 

Qualified participants will be seen by a doctor and receive all study-related exams, care and medications at no cost. Compensation for travel is available.
 

Purpose:

The purpose of this research study is to determine an effective dose of piromelatine, based on results of safety and efficacy on participants with mild dementia due to Alzheimer’s disease as compared to placebo. 

What is Involved:

If you are determined to be eligible, and agree to participate, you will be randomly assigned (like the flip of a coin) to receive one of three doses (5 mg, 20 mg, or 50 mg) of the investigational drug-piromelatine, or placebo. Study participants have a greater chance of receiving the investigational drug than placebo.

The study will take place over 28 weeks. Participants will have 5-6 visits to the study clinic and weekly telephone calls in between each visit. Each study visit will last approximately 2-3 hours. For each visit, participants will need to come with partner/caregiver who knows them well and can accompany them to clinic visits.

Throughout the study, doctors and the study staff will evaluate the health and progress of all study participants through various tests and assessments during the clinic visits and weekly phone calls. Some of these include, but are not limited to:
•    Review of medical history (including past and current health, medications, or treatments) 
•    Physical exams
•    Vital signs measurements
•    Reviews of current medications
•    Blood and urine sample collections
•    Tests that measure mental skills and memory
 

 SELECT A SITE BELOW 

United States

ReCOGNITION - Amherst

Amherst, NY 14226, United States
Dent Neurologic Institute

ReCOGNITION - Bellflower

Bellflower, CA 90706, United States
CITrials

ReCOGNITION - Birmingham

Birmingham, AL 35294, United States
University of Alabama at Birmingham

ReCOGNITION - Brooklyn

Brooklyn, NY 11229, United States
Integrative Clinical Trials, LLC

ReCOGNITION - Brooklyn

Brooklyn, NY 11235, United States
SPRI Clinical Trials, LLC

ReCOGNITION - Charleston

Charleston, SC 29401, United States
Roper St. Francis Hospital

ReCOGNITION - Charlotte

Charlotte, NC 28211, United States
New Hope Clinical Research

ReCOGNITION - Chesterfield

Chesterfield, MO 63005, United States
Galen Research

ReCOGNITION - Coconut Creek

Coconut Creek, FL 33066, United States
Pioneer Clinical Research

ReCOGNITION - Columbus

Columbus, OH 43210, United States
Ohio State University

ReCOGNITION - Farmington Hills

Farmington Hills, MI 48334, United States
QUEST Research Institute

ReCOGNITION - Flowood

Flowood, MS 39232, United States
Precise Research Centers

ReCOGNITION - Hallandale Beach

Hallandale Beach, FL 33009, United States
MD Clinical

ReCOGNITION - Hattiesburg

Hattiesburg, MS 39401, United States
Hattiesburg Clinic

ReCOGNITION - Hialeah

Hialeah, FL 33016, United States
Galiz Research

ReCOGNITION - Hialeah

Hialeah, FL 33012, United States
New Life Medical Research Center

ReCOGNITION - Jenkintown

Jenkintown, PA 19046, United States
The Clinical Trial Center, LLC

ReCOGNITION - Lake Charles

Lake Charles, LA 70629, United States
Lake Charles Clinical Trials

ReCOGNITION - Lenexa

Lenexa, KS 66214, United States
Rowe Neurology

ReCOGNITION - Lewisville

Lewisville, TX 75067, United States
Shepherd Clinical Research, LLC

ReCOGNITION - Long Beach

Long Beach, CA 90807, United States
Renew Behavioral Health

ReCOGNITION - Long Beach

Long Beach, CA 90807, CA 90807, United States
Alliance for Wellness - Research

ReCOGNITION - Madison

Madison, WI 53715, United States
SSM Healthy / Dean Medical Group

ReCOGNITION - Media

Media, PA 19063, United States
Suburban Research Associates

ReCOGNITION - Miami

Miami, FL 33137, United States
Miami Jewish Health Systems

ReCOGNITION - Miami

Miami, FL 33136, United States
University of Miami Miller School of Medicine

ReCOGNITION - Miami

Miami, FL 33126, United States
Biomed Research Institute

ReCOGNITION - New York

New York, NY 10022, United States
Manhattan Behavioral Medicine

ReCOGNITION - Norwalk

Norwalk, 06851, United States
Research Center for Clinical Studies (RCCS)

ReCOGNITION - Oklahoma City

Oklahoma City, OK 73112, United States
Red River Medical Research Center