have a family history of Alzheimer’s disease or dementia
can travel to Greensboro for testing on 2 days at beginning, after 6 months, and after 1 year
are not regularly physically active (exercise < 90min/week)
are not displaying symptoms of memory or thinking impairment or depression
are not taking medications that affect thinking or exercise
are healthy enough to exercise at moderate intensity
do not have uncorrected visual or hearing impairment
About the Study:
This is a research project that is designed to test the effects of a 1-year physical activity program on the cognitive performance of adults relative to their risk for Alzheimer’s disease.
Results from this study may help us to understand the benefits of physical activity for persons with a family history of Alzheimer’s disease (AD) relative to a person's genetic risk for AD.
What is Involved:
You will be asked to complete 5 visits over 12-16 months. During data collection visits, you will answer questions about your health, perform cognitive tests, and complete an aerobic fitness test. You will also be asked to provide a blood sample and a saliva sample for APOE genotyping. If you can safely complete an MRI scan, you will be asked to do so. After completing pre-testing, you will be randomly assigned to either a 12-month virtual exercise program (exercise group) or asked to maintain your current level of physical activity for 12 months (control group). The control group will receive a free short-term membership to their local YMCA (or equivalent) upon study completion. All participants will be compensated for data collection visits.
University of North Carolina at Greensboro
Department of Kinesiology
1408 Walker Avenue
Greensboro NC 27402