Finance, Cognition, and Default Network in Aging (FCDNA) - Alhambra, CA

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Finance, Cognition, and Default Network in Aging (FCDNA) - Alhambra, CA

3 years
3+ in person visits
Study Type:
Prevention Studies
Studies for People without Memory Impairment

Eligibility Requirements:

This study is seeking people who are:

  • Cognitively healthy
  • Aged 50 years or older, and
  • Fluent in English

Exclusion criteria:

  • Significant neurological or psychiatric illness,
  • Current or previous substance abuse history, and
  • Current known cognitive impairment

About the Study:

Researchers at USC believe that changes in financial decision making in older age may be linked to cognitive decline and Alzheimer’s disease. The overall goal of this study is to examine characteristics of financial decision making in old age (e.g., experiences of scam, fraud, and financial exploitation) with possible markers of Alzheimer's. Researchers hypothesize certain financial decision making characteristics are associated with greater cognitive decline, greater change in behavioral economic preferences, greater deterioration in brain imaging measures, and greater Alzheimer's genetic risk.


Study findings will inform early detection and intervention programs focused on cognitive health and wellbeing in old age.

What is Involved:

Participants will be divided into two groups: those who have been financially exploited and demographically-matched healthy controls. They will followed for three years. Once every year, participants will complete a 4-hour behavioral session. The behavioral sessions will occur at the USC Department of Family Medicine offices in Alhambra, CA. The behavioral assessments will include standard measures of cognition, health, behavioral economics, and financial status. 

Participants may be asked to participate in a one-hour qualitative follow-up interview based on how they respond to certain questions. 

During the first year only, participant saliva will be collected via cheek swab to obtain genetic data to assess APOE genotype. 

During the first and third year, participants will

complete a 1-hour brain scanning (MRI) session. The scanning session will occur at the USC Center for Imaging Acquisition (CIA).