Diagnosis of dementia due to Alzheimer’s disease (but no diagnosis of other neurological or psychiatric illnesses)
Willing to provide a doctor’s note to confirm diagnosis
Must have normal or corrected-to-normal vision and hearing
Not taking beta-blocker or psycho-active medications (e.g., stimulants, anti-depressants)
Able to go in an MRI scanner (i.e., must not have any metal on or in the body)
About the Study:
During the study, participants will complete a one-hour brain scan in an MRI scanner at the Health Science Campus of University of Southern California. While in the scanner, participants will be asked to rest for short periods of time as well as to complete two short cognitive tasks. The remaining time outside of the scanner will be spent completing computer-based cognitive tasks and questionnaires. The entire study will take three hours to complete and participants will receive a $75 VISA gift card for their time and effort. Parking on campus will also be covered for the day, if required. For more information, please contact the researchers (emotionattention.USC@gmail.com).
The purpose of the study is use brain imaging to advance knowledge surrounding cognitive and emotional functioning in Alzheimer’s disease. We are specifically interested in the locus coeruleus, a brain region that is involved in the physiological responses to stress and emotion and related to a biomarker of Alzheimer’s disease.
What is Involved:
The experiment will involve a single 3-hour session that will be completed at the Health Science Campus of USC and include the following:
A 1-hour brain scan in an MRI scanner
Computer- and paper-based tasks that measure various aspects of cognition
Heart-rate and breathing patterns will be measured non-invasively during the MRI scan