Brain Stimulation for Mild Cognitive Impairment (rTMS-MCI) Study - Palo Alto, CA

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Brain Stimulation for Mild Cognitive Impairment (rTMS-MCI) Study - Palo Alto, CA


Study Status:
Recruiting
Age:
55 to 90
Duration:
7.5 months
Study Type:
Studies for People with Memory Impairment

Eligibility Requirements:

Who can participate?

  • Age 55 to 90 years of age with a slight but noticeable decline in memory.
  • In otherwise good health.
  • Able to safely undergo MRI (e.g. not have a pacemaker)
  • Have a spouse, friend, or relative who is willing to attend some of the study visits at our facility in Palo Alto, CA

About the Study:

rTMS is a non-invasive method of stimulating the brain’s neurocircuitry in a medical office setting.

  • rTMS generates a magnetic field that penetrates the scalp to produce very small electrical currents in the brain.
  • These currents stimulate areas of the brain that are involved in memory, mood, attention, and thinking.
  • The purpose of the study is to determine if repetitive Transcranial Magnetic Stimulation (rTMS)—a method of stimulating the brain—can improve memory and thinking in adults with Mild Cognitive Impairment (MCI).

Purpose:

The purpose of the study is to determine if repetitive Transcranial Magnetic Stimulation (rTMS)—a method of stimulating the brain—can improve memory and thinking in adults with Mild Cognitive Impairment (MCI).

What is Involved:

Each participant will participate in the study for approximately 7 ½ months—including a daily rTMS treatment phase (20 sessions in all), and post-intervention follow-up lasting 6 months.  Participation typically involves a total of 15 study visits: the Screening Visit, a Baseline Visit, 10 Study Treatment Visits, a Post-Treatment visit, then two follow-up visits at 3 months and 6 months.

During the study, you and your study partner will be asked to answer questions about your daily functioning and your behavior.  You will receive tests of your memory and thinking. You will undergo an MRI scan before and after rTMS to take electronic pictures of your brain.
 

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