Alzheimer’s Disease Neuroimaging Initiative (ADNI) - Multiple Locations


  • Location: Multiple Locations
  • Age: 55 to 90
  • Duration: 5+ years
  • Visits: 2 online visits per year, up to 7 in-person visits
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Eligibility Requirements

  • Are 55-90 years old
  • People with no memory problems, mild memory concerns or those with early dementia/Alzheimer’s disease
  • Live within 150 miles of one of our 50+ ADNI clinical sites across the US and Canada
  • Are fluent in English or Spanish
  • Are willing and able to do in-person assessments, memory and other types of tests (if applicable)
  • Have a study partner who can come with you to clinic visits (if applicable)

About the Study:

The ADNI study began in 2004 and is a longitudinal research project, which means we study people over many years. ADNI does this to track changes in a person’s memory and thinking as they age as well as study the physical changes that happen to a person’s brain over time by using imaging scans like MRI (magnetic resonance imaging). See “What is Involved” below for more details. ADNI is an observational study, so no medications or treatments are given as part of the study.

If you choose to join ADNI, you help make a big impact on Alzheimer's research. The data we collect helps researchers better understand aging, memory changes, and Alzheimer's disease. ADNI will share data with the scientific community. This leads to important discoveries about brain aging in older adults.

By studying brain aging in older adults and sharing the knowledge researchers gain, the field can move towards earlier diagnosis, better treatments, and an end to Alzheimer's disease and dementia.


ADNI’s main goals are to:

  1. Improve how doctors diagnose patients with Alzheimer's disease
  2. Provide data to researchers around the world so that together we can find and improve treatments for Alzheimer's disease.

What is Involved:

ADNI has many different tests to study changes in memory and thinking. First, ADNI participants answer questions about themselves and their everyday lives. ADNI also uses memory tests to learn what problems they may be having with thinking and memory. Some of these tests are online, and others are done with study staff at a clinic near you.

Some participants will also be asked to provide a blood sample. The sample will be tested for the presence of different biological compounds. This will be used to study new ways of finding signs of future cognitive decline. This study also asks some participants to come to clinical sites for more in-depth tests. In the clinic, the study uses MRI (magnetic resonance imaging) or PET (positron emission tomography) scans to take pictures of your brain.

Eligible participants who complete certain phases of the ADNI study may be paid.

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