To be eligible for the AHEAD Study, you must:
Participants will be compensated for their time.
The AHEAD Study is a new trial aiming to prevent Alzheimer’s disease. It is evaluating whether an investigational treatment (BAN2401 (lecanemab)) can lower the amount of amyloid in the brain and how that impacts decline in memory loss due to Alzheimer’s.
Studies have shown that changes caused by Alzheimer’s occur in the brain many years before a person shows symptoms of the disease.
The purpose of the AHEAD Study is to determine whether intervention with the investigational anti-amyloid treatment, BAN2401 (lecanemab), can slow the earliest brain changes associated with Alzheimer’s disease and help to prevent the associated memory loss, especially if started early, before symptoms are clinically apparent. The AHEAD Study will help researchers understand what early Alzheimer’s disease changes in the brain, such as specific levels of amyloid, detected with imaging and other biomarker tests, are associated with cognitive decline.
The AHEAD Study may also help researchers understand why some groups are at increased risk and find the most appropriate treatment for all individuals.
If you qualify for the AHEAD Study, you will receive the study treatment (investigational treatment [BAN2401 (lecanemab)] or placebo) intravenously (IV) every other week or monthly, depending on whether you are in AHEAD-3 or AHEAD-45.
Please see study website for additional information: aheadstudy.org