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Risk Factors

Biomarkers – Leading the Way toward Alzheimer’s Early Detection, Prevention and Treatment

You might be familiar with biomarkers such as cholesterol levels, blood pressure numbers and body temperature. But what about amyloid and tau? How might these biomarkers lead the way to detecting, preventing and treating this and related devastating diseases.

Borrowing from the cancer playbook to find treatment for Alzheimer's disease

It's been notoriously difficult to develop medicines for Alzheimer's disease, the sixth leading cause of death in the United States. Each year, it seems, pharmaceutical companies release data from studies of promising drug candidates that merit only a collective sigh of disappointment. In search of fresh ideas, researchers have begun to borrow a phrase or two from the more familiar language of cancer treatment.

Ask the Expert: GeneMatch

Dear Dr. Roberts,

My father recently enrolled in GeneMatch, a new Alzheimer’s Prevention Registry program. He did a cheek swab and is waiting to be “matched” with appropriate studies. What are the next steps for my father? How can he get the results of the genetic screening so he’ll know if he carries the gene that increases the potential for Alzheimer’s disease?

Ask The Expert: Can a Brain Scan Diagnose Alzheimer's?

Dear Dr. Jagust,
I thought the only way to diagnosis Alzheimer’s disease definitively, unfortunately, is through an autopsy. Recently, a friend mentioned imaging studies, like PET scans, are being researched for this purpose. Can you explain the role of PET in diagnosing dementia? Will it replace the autopsy?


What Science Actually Tells Us Can Affect Our Risk Of Alzheimer's Disease

Scientists have determined that there some factors that may play a role in slowing down the symptoms of Alzhiemer’s disease that are in our control, including diet, exercise, heart health, education/mental activity and mental health.

Calm down: Herpes probably isn’t going to give you Alzheimer’s

An editorial on previous research outlined that herpes could cause Alzheimer’s. Scientists say that that it’s all correlative and that there’s no true evidence showing the link between the two.

Screening for Alzheimer's Gene Tests the Desire to Know

The extended Reiswig family has a mutated gene that is passed down from parent to child. In Marty and Matt Reiswig’s case, they inherited the gene and have a 50-50 chance of getting Alzheimer’s with absolute certainty. The two share how they have dealt with deciding if they’ll find out and the effects of living with Alzheimer’s.

Ask the Expert - High Blood Pressure and Dementia

Dear Dr. DeCarli,
High blood pressure runs in my family. My brother and I are in our 40s and we’re both watching our blood pressure creep up. At my last physical, my doctor said I was pre-hypertensive. My brother says high blood pressure can contribute to dementia. Is it true? What can my brother and I do to manage our blood pressure?


Ending the Silence on High Blood Pressure and Brain Health

High blood pressure has earned the title of “silent killer” because it typically has no symptoms until after it has done significant damage to the heart and arteries. Now there’s evidence that links high blood pressure to our brains and dementia.

Are Women the Key to Unlocking Alzheimer's

Not only are women more likely to get Alzheimer's than men, but recent studies suggest the disease does its work more swiftly in women, causing them to decline faster -- and farther -- than men do, at least in the beginning.