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Risk Factors

Brain Plaque Buildup Tied to Alzheimer's Found in Young Adults

New research is showing brain-plaque buildup has been identified in men and women as young as twenty years old.

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Living with a 91% Chance of Alzheimer's

Jamie Tyrone, 54, found out six years ago that her genetic status puts her at the greatest risk of developing Alzheimer’s disease. Jamie is involved with research at Banner Alzheimer’s Institute.

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Ask the Expert: Early Onset Alzheimer's

Eric M. Reiman, MD, is this month's expert. An internationally recognized Alzheimer's disease researcher, Dr. Reiman is executive director of Banner Alzheimer's Institute; clinical director of the Neurogenomics Division at the Translational Genomics Research Institute (TGen); professor of psychiatry at the University of Arizona; and director of the Arizona Alzheimer's Consortium.

Dear Dr. Reiman,

I recently saw the movie "Still Alice" and it got me interested in learning more about early-onset Alzheimer's disease. How is it different than late onset? What kind of research is being done to stop Alzheimer's?



Solving the Alzheimer's Mystery | Part Two: The Cure?

Scientists knew families in Colombia were cursed with early Alzheimer's disease. Pharmaceutical companies had made drugs to treat protein buildup in the brain, but drugs tests were failing. Then came a new idea, from Banner Alzheimer's Institute.

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Inside the Science of Alzheimer's Prevention

Families stalked by a remorseless killer that steals loved ones years before their time. Teams of scientists and health care professionals dedicated to finding the truth. If their work succeeds, the consequences could be profound -- both for the families involved and for the entire world.

It sounds like a Hollywood thriller, but this story is very real, as a new series of articles in the Arizona Republic called "Solving the Alzheimer's mystery" shows. The killer? Early-onset Alzheimer's, which strikes people in their 40s, decades before the disease shows symptoms in most who develop it. The families? Clustered in a ring of towns and villages around Medellin, Colombia and bonded together both by a common ancestry and by a genetic predisposition to early-onset Alzheimer's. The research study? The Alzheimer's Prevention Initiative's Autosomal Dominant Alzheimer's Disease (ADAD) prevention trial currently in progress.

Arizona Republic reporter Ken Alltucker has crafted both a terrific story and a great introduction to the role of genetic testing in Alzheimer's prevention research, and we hope you'll read his work and spread the word. The series began on February 15 and continues on Wednesday, February 18 and Sunday, February 22.

• Read the "Solving the Alzheimer's mystery," the first installment in the series

• Share the article on Facebook and Twitter




Update: Part Two of the Arizona Republic series is now online. Read "The Cure?" for more about how Banner Alzheimer's Institute pursued a bold research idea - testing a promising drug as a means to prevent the disease – in a population with a genetic mutation that destined them to get Alzheimer's as early as age 45.

Solving the Alzheimer's Mystery

In Colombia, where families with a genetic mutation are doomed to face Alzheimer's, a $100 million drug trial is under way. The first question is whether the test can change the families' future. The bigger question is what it will mean for the rest of the world.

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Catching Alzheimer’s Before Memory Slips

A three-year study called Nuerotrack has been developed that uses an eye-tracking device to capture eye movements. This online test could become an affordable tool for widespread screening, enabling doctors to see who is at risk for Alzheimer's three to six years before symptoms emerge.

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Life-Saving Answers Exist; the Key Is Continuing the Search

Research is the engine that propels science. Every mile we've gained in the treatment and prevention of all diseases comes from researchers discovering new way of doing things, or ways to do them better.

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Our 2014 Top 5 Scientific Advances and Emerging Trends

We're weeks into 2015 and February looms on the horizon, so it's an ideal time to assess if you're on track with your New Year's fitness and health improvement goals. At the Alzheimer's Prevention Registry, we took on a different kind of exercise in January. Our team looked back at 2014 to consider how research into preventing, diagnosing and treating Alzheimer's disease fared during the year.

While the year was filled with more interesting research results and important scientific findings than we can include, we're focusing on five we believe are of most significance to Alzheimer's Prevention Bulletin readers.

Let's take a look at Alzheimer's disease research and prevention developments in 2014. What a year it was!