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The Alzheimer’s Prevention Registry: A Large Internet-Based Participant Recruitment Registry to Accelerate Referrals to Alzheimer’s- Focused Studies

Recruitment for Alzheimer’s disease (AD) focused studies, particularly prevention studies, is challenging due to the public’s lack of awareness about study opportunities coupled with studies’ inclusion and exclusion criteria, resulting in a high screen fail rate. 

Scientists study whether aspirin can reduce risk of dementia

Aspirin’s ability to reduce inflammation made it a useful tool in reducing the risk of repeat heart attack and stroke. Can it also reduce or prevent the inflammation in the brain often associated with dementia and Alzheimer’s disease? Read the findings of a five-year study on aspirin and dementia.

The Future of Medicine: A New Era for Alzheimer’s

It is time to start anew. More than a century after neuropathologist Alois Alzheimer gave the first scientific talk describing the disease that bears his name today, we have no good treatments for this thief of minds, and we certainly have no cure. Today 40 million to 50 million people worldwide suffer from Alzheimer's disease and other dementias. The drugs doctors have tried, aimed at a single type of lesion, have repeatedly and agonizingly fallen short. Now scientists are beginning to say it is high time for a fresh approach to the illness.

Caring for Persons with Alzheimer’s Disease Amid the COVID-19 Crisis

Living with Alzheimer’s or any form of dementia is difficult enough. Add the stress of a global pandemic to the mix and you’re bound to have a few more questions. We spoke with Lori Nisson, the Family & Community Services director at the Banner Alzheimer’s Institute to gain some insight for maintaining routine, connection and safety in unsettling times.

Two views on Alzheimer's biomarkers: Eyeing changes in vision or pupils

Findings in two separate NIA-funded papers focus on different ways to develop noninvasive, less expensive ways to detect very early-stage Alzheimer’s disease in cognitively healthy people. The studies suggest that changes in vision and pupil responses may be effective biomarkers for Alzheimer’s in those at greater risk for dementia.

Alzheimer's patients isolated due to coronavirus finding support in virtual therapy

The Alzheimer’s Foundation of America (AFA) was founded in 2002 with the goal of providing a community for individuals, families and caregivers affected by Alzheimer’s disease and related dementias. As coronavirus isolates millions of Americans across the country, the AFA is working harder than ever to ensure that some of our nation’s most vulnerable still have a support system.

Large-scale analysis links glucose metabolism proteins in the brain to Alzheimer’s disease biology

In the largest study to date of proteins related to Alzheimer’s disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers. The findings suggest that sets of proteins that regulate glucose metabolism, together with proteins related to a protective role of astrocytes and microglia — the brain’s support cells — are strongly associated with Alzheimer’s pathology and cognitive impairment.

Mild Behavioral Impairment Can Help Predict Alzheimer’s, According to Study

In the late 1890s, a railroad worker in Frankfurt Germany noticed that his wife, Auguste Deter, was behaving oddly. Gradually her anxiety and mood changes gave way to memory loss, delusions and other signs of dementia. Committed to an institution in the care of Dr. Alois Alzheimer, Deter became the first person diagnosed with Alzheimer’s disease. A new study establishes that even her subtle, early shifts in behavior —  mild behavioral impairment — were scientifically linked to what was to come.

More Evidence Mediterranean Diet Fights Cognitive Impairment

The next time you’re deciding between a halibut or a steak filet, there’s now one more reason to opt for fish over red meat. A new study published in Alzheimer’s and Dementia builds on past findings that lifestyle choices may help fight cognitive impairment and prevent Alzheimer’s disease.

New Genetic Variant Discovered to Protect Against Risk of Alzheimer’s Gene ApoE4

The Alzheimer’s gene, known as ApoE4, is one of the the largest genetic risk factors for later onset Alzheimer’s disease. Carrying one copy of the gene triples the risk of developing Alzheimer’s, while two copies increase one’s risks more than 12 times.  Scientist now think they may have found a new gene known as KL-VS that may counter the elevated risk associated with ApoE4.