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Researchers Explore Why Women's Alzheimer's Risk Is Higher Than Men's

Scientists are beginning to understand why Alzheimer's disease affects more women than men and why the disease seems to progress more quickly in women's brains.

A Blood Test Can Predict Dementia. Trouble Is, There's No Cure

Nobel prizewinner Koichi Tanaka says the predictive blood test for Alzheimer’s disease he and colleagues spent almost a decade developing is a double-edged sword.

Alzheimer’s Tests: What Tests Are Available and How Accurate Are They?

There is no single test available to diagnose Alzheimer’s. Instead, physicians rely on several diagnostic tools and medical criteria to ascertain whether a person may be suffering from the disease. Unfortunately, the most widely recognized diagnostic tests for Alzheimer’s are inconclusive, at best. And while neurologists and geriatricians can usually tell if a patient is suffering from dementia, figuring out its cause is challenging, and may lead to a false Alzheimer’s diagnosis.

Herpes Accelerates the Development of Alzheimer’s, Finds New Animal Study

Test tube and mice research has found that herpes and other viruses speed up the development of neurodegenerative diseases like Alzheimer’s.

Tau Protein and Alzheimer’s: Does This Protein Hold the Key to a Cure?

Tau protein tangles (or neurofibrillary tangles) are a hallmark of Alzheimer’s disease, but what role do they play? First, you need to understand how a disease like Alzheimer’s spread across the brain. Degenerative diseases including Alzheimer’s, Parkinson’s and other dementias are “prion-like,” meaning they happen because proteins in the brain misfold and change their structure. Once one protein misfolds, the same process can spread to other parts of the brain, causing many cells to misfold. That results in what we call tau tangles. 

The Link Between Brain Plaques and Alzheimer’s: Everything You Need to Know

Researchers have been focusing on how brain plaque contributes to Alzheimer’s disease since Dr. Alois Alzheimer noticed strange clumps in a patient’s brain after her death. When toxic proteins like beta-amyloid and tau accumulate in the brain, they form plaques and tangles. Some researchers suggest these plaques and tangles resemble Swedish meatballs when examined under a microscope. Scientists are still looking into why some people have more plaques and tangles in their brains than others. However, they believe genetics and lifestyle choices play a role.

Alzheimer’s research is getting a reboot at small companies focused on the immune system

A health-care start-up called Partner Therapeutics began last year with a single product: a leukemia medicine approved in 1991 that doctors rarely prescribe anymore. The drug, Leukine, made so little money that its previous owner did not even bother to disclose sales. It just dumped them on revenue reports under “other.”

A Genetic Test That Reveals Alzheimer's Risk Can Be Cathartic Or Distressing

In a waiting room at the Banner Alzheimer's Institute in Phoenix, a 74-year-old woman named Rubie is about to find out whether she has a gene that puts her at risk for Alzheimer's.