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Prevention

Large-scale analysis links glucose metabolism proteins in the brain to Alzheimer’s disease biology

In the largest study to date of proteins related to Alzheimer’s disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers. The findings suggest that sets of proteins that regulate glucose metabolism, together with proteins related to a protective role of astrocytes and microglia — the brain’s support cells — are strongly associated with Alzheimer’s pathology and cognitive impairment.

Staying Engaged During Coronavirus Isolation: Home Therapeutic Activities for Individuals Living with Alzheimer’s Disease

As the Coronavirus outbreak forces many families to stay confined at home, the Alzheimer’s Foundation of America (AFA) is providing families affected by Alzheimer’s disease with information about simple therapeutic activities they can do to keep their loved one engaged and active while at home.

Mild Behavioral Impairment Can Help Predict Alzheimer’s, According to Study

In the late 1890s, a railroad worker in Frankfurt Germany noticed that his wife, Auguste Deter, was behaving oddly. Gradually her anxiety and mood changes gave way to memory loss, delusions and other signs of dementia. Committed to an institution in the care of Dr. Alois Alzheimer, Deter became the first person diagnosed with Alzheimer’s disease. A new study establishes that even her subtle, early shifts in behavior —  mild behavioral impairment — were scientifically linked to what was to come.

More Evidence Mediterranean Diet Fights Cognitive Impairment

The next time you’re deciding between a halibut or a steak filet, there’s now one more reason to opt for fish over red meat. A new study published in Alzheimer’s and Dementia builds on past findings that lifestyle choices may help fight cognitive impairment and prevent Alzheimer’s disease.

New Genetic Variant Discovered to Protect Against Risk of Alzheimer’s Gene ApoE4

The Alzheimer’s gene, known as ApoE4, is one of the the largest genetic risk factors for later onset Alzheimer’s disease. Carrying one copy of the gene triples the risk of developing Alzheimer’s, while two copies increase one’s risks more than 12 times.  Scientist now think they may have found a new gene known as KL-VS that may counter the elevated risk associated with ApoE4.

‘A4’ Study Aims to Target Amyloid in the Earliest Stages of Alzheimer’s

Targeting beta-amyloid protein before symptoms of cognitive decline or Alzheimer’s appear is the goal of one trial out of the National Institute on Aging (NIA), which recently released its first data set from its prevention trial.

Lori Nisson: How to Create a Caregiving Plan for COVID-19

As COVID-19 continues to spread, particularly hitting vulnerable populations like elderly in nursing homes, caregiving for a loved one with dementia may feel overwhelming. But creating a plan to manage themselves and their loved ones during the pandemic can help.

Lack of Sleep Could Hurt The Brain’s Ability To Clear Out Toxins

The biology of sleep has long been a mystery. Exactly how brain and neurodegenerative diseases like Alzheimer’s might be biologically connected to sleeping disorders has never been entirely clear.

Primary care doctors expect to see increase in patients with dementia in next five years

More than 5 million Americans suffer from Alzheimer’s disease and the number is expected to rise as high as 13.8 million by 2050. Yet, according to the latest Alzheimer’s Association Facts and Figures report, half of all primary care physicians feel the medical community is not prepared to meet the demand. Learn more about the projected incidence of Alzheimer’s dementia and the burden it places on caregivers and the health care system.