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Alzheimer's Prevention Bulletin

Alzheimer’s Researchers Face A Shakespearean-Like Question

Imagine this: You’re an Alzheimer’s researcher conducting a study that includes genetic testing to determine if participants carry the APOE4 gene, which is linked to both Alzheimer’s disease and heart disease. Do you inform participants who carry the APOE4 gene about their risk for these conditions? What impact might this knowledge have on the psychological well-being and health behaviors of your study participants? This issue of Alzheimer’s Prevention Bulletin looks at recent research on how people react to such information.

Ask the Expert: Funding Alzheimer's Research and What it Means for Me?

Our June expert is Heather M. Snyder, PhD, Senior Director of Medical and Scientific Operations for the Alzheimer’s Association. Based in Chicago, Illinois, the Alzheimer’s Association is the leading voluntary health organization in Alzheimer’s care, support and research. 

Falling into Place: The Domino Theory at Work for Alzheimer’s Research

Tap the lead domino in a line of the tiles and you’re likely to start a chain reaction. When the tiles are metaphors for nations, events or ideas, social scientists call this the domino theory. Alzheimer’s researchers are hoping for a domino-like reaction of support if Congress approves increased funding for Alzheimer’s disease research. This issue of Alzheimer’s Prevention Bulletin looks at how a proposed $400 million increase for Alzheimer’s disease research could spark interest in participating in clinical studies.  

Building a Better Clinical Trial

There are more clinical trials focused on preventing Alzheimer’s disease than ever before, with even more studies in the early planning stages. Once these studies are launched, researchers pursue an often slow process of recruiting people for their respective research studies. This issue of Alzheimer’s Prevention Bulletin looks at factors that entice or deter research recruitment. Come consider what would attract you to a clinical trial. 

Ask the Expert: Transparent Studies

Dear Dr. Grill,

My Mom is interested in taking part in a “transparent” preclinical trial on Alzheimer’s disease. As part of the study, she would undergo Positron Emission Tomography, also called a PET scan. Because this is a transparent study, I understand she’ll receive the results of this PET scan. What kind of support should I seek for my Mom if the results show she has amyloid in her brain, a biomarker for Alzheimer’s? Are transparent studies becoming more common for Alzheimer’s disease?​

Ask The Expert: Can a Brain Scan Diagnose Alzheimer's?

Dear Dr. Jagust,
I thought the only way to diagnosis Alzheimer’s disease definitively, unfortunately, is through an autopsy. Recently, a friend mentioned imaging studies, like PET scans, are being researched for this purpose. Can you explain the role of PET in diagnosing dementia? Will it replace the autopsy?
Sincerely,
Meg

 

Researchers Harness the Power of PET

Researchers are using the power of positron emission tomography (PET) imaging to solve the mysteries of Alzheimer’s dementia. This issue of Alzheimer’s Prevention Bulletin features a recent study involving a new type of PET imaging that has helped take us a step closer to understanding the precise origin of Alzheimer’s dementia.

Ask the Expert - High Blood Pressure and Dementia

Dear Dr. DeCarli,
High blood pressure runs in my family. My brother and I are in our 40s and we’re both watching our blood pressure creep up. At my last physical, my doctor said I was pre-hypertensive. My brother says high blood pressure can contribute to dementia. Is it true? What can my brother and I do to manage our blood pressure?

 

Ending the Silence on High Blood Pressure and Brain Health

High blood pressure has earned the title of “silent killer” because it typically has no symptoms until after it has done significant damage to the heart and arteries. Now there’s evidence that links high blood pressure to our brains and dementia.

Volunteering Benefits Your Brain

One of the 10 most popular New Year’s resolutions – volunteering to help others achieve their dreams – may also benefit your brain. Recent research shows meaningful volunteer activities may help older adults halt brain atrophy and improve memory.